"Take the Vax" revolves around a young vaccine skeptic named Mark, played by Fesal Jaber, in a not-so-distant future where the COVID-19 pandemic had subsided. As he goes about his daily chores and activities, Mark sees a variety of vaccine messages all around the city, and he tries to run away from them as much as he can, but the looming figure of “The Vax”, played by Elijah Jaber, follows him everywhere. People on the streets and on public transportation ostracize him for being rebellious and not doing his part in combating the virus. As he slowly runs out of basic resources that he can no longer fetch for himself, he realizes that he has no other choice but to take the vax.