Traumatic Brain Injury survivor Derek Dabkoski enrolls in an experiment to have stem cells injected directly into the affected area of his brain, with the hopes he might regain the functionality lost after he was brutally attacked and left for dead on the streets of San Francisco a decade ago. Although Derek sees his participation in the study as a chance to recover physically, he comes to realize it will also give him the strength needed to help his wife Nadia get her unrightfully denied Green Card and prepare for their first born child. Derek Changes His Mind paints the intimate portrait of a family living life at the crossroads of medical science and immigration reform.