Dennis Peron is San Francisco's biggest pot dealer. But when the AIDS epidemic sweeps through his community, Peron realizes that marijuana is more than a good time—it’s medicine. In the wake of his lover’s death, Peron opens the Cannabis Buyers’ Club, a five-story dispensary complete with rainbow murals, drag shows, and doctors onsite. Law enforcement launches a multimillion dollar investigation into the club, but Peron has even larger aspirations, writing a landmark political initiative and leading the fight for change.