Connection | Isolation presents eight intimate portraits of trans and post-gender individuals navigating the challenges of the COVID-19 pandemic. Amidst moments of connection and isolation, these participants reveal a deepening awareness of gender, their bodies, and trans community. Participants express how Asian Americans faced escalating violent racism during the pandemic, how Black Americans and allies rose in opposition to white supremacist police-state violence in 2020, and the exclusion disabled people feel from a society that refuses basic protections. Created by an all trans and queer crew, this hybrid documentary film interlaces portraits with reenactments, integrating archival material documenting what so many experienced and many still do. Connection | Isolation witnesses the profound ways that, despite physical separation, trans community-building has been centered. This documentary invites viewers to witness the strength of connection as an act of resistance, offering care in the face of crisis, and using reflection as a path toward healing.